{"number":"CN117821469B","kindCode":"B","documentType":"grant","title":{"original":"一种鸡TRIM45截短体重组蛋白或其多克隆抗体的应用","english":"Application of chicken TRIM45 truncated recombinant protein or polyclonal antibody thereof"},"abstract":{"original":"本发明公开了一种鸡TRIM45截短体重组蛋白或其多克隆抗体的应用。本发明公开了一种鸡TRIM45基因、重组载体、截短体重组蛋白或其多克隆抗体在制备抗禽白血病病毒相关药物中的应用，所述鸡TRIM45基因Genbank登录号为XM_040707211。本发明构建的鸡TRIM45截短体重组蛋白，避免了全长表达稳定性的缺点，同时免疫效果更加稳定且抗体水平较高。同时本发明制备的真核表达载体和多克隆抗体可应用于鸡TRIM45对ALV‑J复制调控的机制研究，具有深远意义，弥补了鸡TRIM45抗体制备及研究的空白；为鸡抗ALV‑J感染和免疫调节的机制研究提供新思路。","english":"The present invention discloses an application of a chicken TRIM45 truncated recombinant protein or a polyclonal antibody thereof. The present invention discloses an application of a chicken TRIM45 gene, a recombinant vector, a truncated recombinant protein or a polyclonal antibody thereof in the preparation of anti-avian leukosis virus related drugs, and the chicken TRIM45 gene Genbank accession number is XM_040707211.…"},"applicants":["Yangzhou University"],"inventors":["陈世豪","王佳兴","常国斌","平玉宇","白皓","黄烜"],"filingDate":"2023-11-22","publicationDate":"2024-08-02","grantDate":"2024-08-02","verifiedWithOffice":false,"pdfUrl":"https://downloadpatent.com/pdf/CN117821469B.pdf","pages":{"en":"https://downloadpatent.com/patent/CN117821469B","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/CN117821469B","ja":"https://downloadpatent.com/ja/patent/CN117821469B"}}