{"number":"US12696897B2","kindCode":"B2","documentType":"grant","title":{"original":"Cryopreserving macrophages","english":"Cryopreserving macrophages"},"abstract":{"original":"The present invention relates to a method of improving the viability of macrophages subjected to cryopreservation, particularly for macrophages which are to be used in therapy, wherein the method comprises a step of maintaining the macrophages at a temperature of 2-12° C. for at least 30 minutes during either freezing or thawing procedures. Following the holding step during cooling, a cooling rate of 1 to 5° C. is used until the macrophages in a medium are frozen. For thawing the macrophages, a warming rate of 1 to 5° C. per minute is used until a temperature of 35-37° C. is reached.…","english":"The present invention relates to a method of improving the viability of macrophages subjected to cryopreservation, particularly for macrophages which are to be used in therapy, wherein the method comprises a step of maintaining the macrophages at a temperature of 2-12° C. for at least 30 minutes during either freezing or thawing procedures. Following the holding step during cooling, a cooling rate of 1 to 5° C. is used until the macrophages in a medium are frozen. For thawing the macrophages, a warming rate of 1 to 5° C. per minute is used until a temperature of 35-37° C. is reached.…"},"applicants":["The University Court of The University of Edinburgh"],"inventors":["Stuart Forbes","Lara Campana","Benjamin Dwyer","John Campbell","Alasdair Fraser"],"filingDate":"2022-11-25","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12696897B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12696897B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12696897B2","ja":"https://downloadpatent.com/ja/patent/US12696897B2"}}