{"number":"US12697308B2","kindCode":"B2","documentType":"grant","title":{"original":"Thermostable lipid nanoparticle and methods of use thereof","english":"Thermostable lipid nanoparticle and methods of use thereof"},"abstract":{"original":"The present disclosure provides, among other things, a lipid nanoparticle adjuvant composition. The present disclosure provides pharmaceutical compositions that include a stable lipid nanoparticle adjuvant and human papillomavirus (HPV) virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82.","english":"The present disclosure provides, among other things, a lipid nanoparticle adjuvant composition. The present disclosure provides pharmaceutical compositions that include a stable lipid nanoparticle adjuvant and human papillomavirus (HPV) virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82."},"applicants":["Merck Sharp & Dohme LLC"],"inventors":["Andrew Bett","Izzat T. Raheem","Jason W. Skudlarek"],"filingDate":"2022-08-17","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12697308B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12697308B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12697308B2","ja":"https://downloadpatent.com/ja/patent/US12697308B2"}}