{"number":"US12697331B2","kindCode":"B2","documentType":"grant","title":{"original":"Methods of use of T-type calcium channel modulators","english":"Methods of use of T-type calcium channel modulators"},"abstract":{"original":"Described herein, in part, are methods useful for preventing and/or treating a disease or condition relating to aberrant function or activity of a T-type calcium channel, such as psychiatric disorders (e.g., mood disorder (e.g., major depressive disorder)), pain, tremor (e.g., essential tremor), seizures (e.g., absence seizures), epilepsy, or an epilepsy syndrome (e.g., juvenile myoclonic epilepsy). The present invention further comprises methods for modulating the function of a T-type calcium channel and methods of administering a titrated dosage of a T-type calcium channel antagonist.","english":"Described herein, in part, are methods useful for preventing and/or treating a disease or condition relating to aberrant function or activity of a T-type calcium channel, such as psychiatric disorders (e.g., mood disorder (e.g., major depressive disorder)), pain, tremor (e.g., essential tremor), seizures (e.g., absence seizures), epilepsy, or an epilepsy syndrome (e.g., juvenile myoclonic epilepsy). The present invention further comprises methods for modulating the function of a T-type calcium channel and methods of administering a titrated dosage of a T-type calcium channel antagonist."},"applicants":["PRAXIS PRECISION MEDICINES, INC."],"inventors":["Kiran Reddy","Gabriel Maurice Belfort","Bernard Ravina","Marion Wittmann"],"filingDate":"2022-10-27","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12697331B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12697331B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12697331B2","ja":"https://downloadpatent.com/ja/patent/US12697331B2"}}