{"number":"US12697343B2","kindCode":"B2","documentType":"grant","title":{"original":"Intravenous istaroxime for the treatment of acute heart failure","english":"Intravenous istaroxime for the treatment of acute heart failure"},"abstract":{"original":"Described herein are methods of treating acute heart failure in a subject in need thereof, comprising administering a therapeutically effective amount of istaroxime by intravenous infusion over a period of at least 24 hours wherein the therapeutically effective amount of istaroxime is between about 0.1 μg/kg/min and about 3.0 g/kg/min; and wherein the subject's acute heart failure is treated.","english":"Described herein are methods of treating acute heart failure in a subject in need thereof, comprising administering a therapeutically effective amount of istaroxime by intravenous infusion over a period of at least 24 hours wherein the therapeutically effective amount of istaroxime is between about 0.1 μg/kg/min and about 3.0 g/kg/min; and wherein the subject's acute heart failure is treated."},"applicants":["Seismic Pharmaceuticals Operations LLC"],"inventors":["Giuseppe Bianchi","Patrizia Ferrari","Mara Ferrandi","Paolo Barassi"],"filingDate":"2023-07-19","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12697343B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12697343B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12697343B2","ja":"https://downloadpatent.com/ja/patent/US12697343B2"}}