{"number":"US12697349B2","kindCode":"B2","documentType":"grant","title":{"original":"Compositions and methods for treating RAS-mutant cancers","english":"Compositions and methods for treating RAS-mutant cancers"},"abstract":{"original":"The present disclosure relates generally to compositions and methods for the treatment of a RAS-mutant cancer. In particular, the present technology relates to administering a therapeutically effective amount of one or more TXNRD1 inhibitors to a subject diagnosed with, or at risk for a RAS-mutant cancer (e.g., RAS-mutant pancreatic cancer).","english":"The present disclosure relates generally to compositions and methods for the treatment of a RAS-mutant cancer. In particular, the present technology relates to administering a therapeutically effective amount of one or more TXNRD1 inhibitors to a subject diagnosed with, or at risk for a RAS-mutant cancer (e.g., RAS-mutant pancreatic cancer)."},"applicants":["ALGEN BIOTECHNOLOGIES, INC.","MEMORIAL SLOAN KETTERING CANCER CENTER"],"inventors":["Chun-Hao HUANG","Spencer Charles KNIGHT","Scott LOWE"],"filingDate":"2021-10-19","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12697349B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12697349B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12697349B2","ja":"https://downloadpatent.com/ja/patent/US12697349B2"}}