{"number":"US12697377B2","kindCode":"B2","documentType":"grant","title":{"original":"Therapeutic anticancer neoepitope vaccine","english":"Therapeutic anticancer neoepitope vaccine"},"abstract":{"original":"The present invention relates to an anticancer vaccine which includes polynucleotides or polypeptides, methods of treatment of cancer wherein such an anticancer vaccine is used as well as methods for producing the vaccine. The vaccine includes a polynucleotide with a nucleotide sequence encoding a targeting unit, a dimerization unit, a first linker and an antigenic unit. The antigenic unit includes from 3 to 50 antigenic subunits separated by a second linker with each antigenic subunit having at least a part of a cancer neoepitope sequence.…","english":"The present invention relates to an anticancer vaccine which includes polynucleotides or polypeptides, methods of treatment of cancer wherein such an anticancer vaccine is used as well as methods for producing the vaccine. The vaccine includes a polynucleotide with a nucleotide sequence encoding a targeting unit, a dimerization unit, a first linker and an antigenic unit. The antigenic unit includes from 3 to 50 antigenic subunits separated by a second linker with each antigenic subunit having at least a part of a cancer neoepitope sequence.…"},"applicants":["Nykode Therapeutics ASA"],"inventors":["Stine Granum","Elisabeth Stubsrud","Agnete Brunsvik Fredriksen"],"filingDate":"2024-06-10","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12697377B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12697377B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12697377B2","ja":"https://downloadpatent.com/ja/patent/US12697377B2"}}