{"number":"US12697387B2","kindCode":"B2","documentType":"grant","title":{"original":"Chimeric antigen receptors targeting CD19 and use thereof","english":"Chimeric antigen receptors targeting CD19 and use thereof"},"abstract":{"original":"The presently disclosed subject matter provides chimeric antigen receptors (CARs) that specifically target CD19 and cells comprising such CD19-targeted CARs. The presently disclosed subject matter further provides uses of the CD19-targeted CARs for treatment, e.g., for treating blood cancer.","english":"The presently disclosed subject matter provides chimeric antigen receptors (CARs) that specifically target CD19 and cells comprising such CD19-targeted CARs. The presently disclosed subject matter further provides uses of the CD19-targeted CARs for treatment, e.g., for treating blood cancer."},"applicants":["MILLENNIUM PHARMACEUTICALS, INC.","MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES","SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH","MEMORIAL SLOAN-KETTERING CANCER CENTER"],"inventors":["Judith FEUCHT","Jorge MANSILLA-SOTO","Isabelle RIVIERE","Michel SADELAIN","Loic VINCENT","Gary SHAPIRO","Mei Rosa NG","Dan TAVARES","Xingyue HE"],"filingDate":"2022-10-24","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12697387B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12697387B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12697387B2","ja":"https://downloadpatent.com/ja/patent/US12697387B2"}}