{"number":"US12697394B2","kindCode":"B2","documentType":"grant","title":{"original":"Muscle targeting complexes and formulations for treating myotonic dystrophy","english":"Muscle targeting complexes and formulations for treating myotonic dystrophy"},"abstract":{"original":"Aspects of the disclosure relate to complexes and other aspects relate to formulations (e.g., aqueous, lyophilized forms) comprising such complexes comprising an oligonucleotide (e.g., useful for targeting DMPK) covalently linked to an antibody (e.g., anti-TfR1 antibody).","english":"Aspects of the disclosure relate to complexes and other aspects relate to formulations (e.g., aqueous, lyophilized forms) comprising such complexes comprising an oligonucleotide (e.g., useful for targeting DMPK) covalently linked to an antibody (e.g., anti-TfR1 antibody)."},"applicants":["Dyne Therapeutics, Inc."],"inventors":["Scott Hilderbrand","Timothy Weeden","John Najim","Stefano Zanotti","Romesh R. Subramanian","Mohammed T. Qatanani","Cody A. Desjardins","Kim Tang","Brendan Quinn"],"filingDate":"2025-08-21","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12697394B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12697394B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12697394B2","ja":"https://downloadpatent.com/ja/patent/US12697394B2"}}