{"number":"US12697399B2","kindCode":"B2","documentType":"grant","title":{"original":"Microdystrophin gene therapy constructs and uses thereof","english":"Microdystrophin gene therapy constructs and uses thereof"},"abstract":{"original":"Provided are gene constructs that encode a microdystrophin protein for use in gene therapy. The microdystrophin gene constructs and expression cassettes were engineered for improved therapy with respect to efficacy, potency and safety to the subject when expressed by a viral vector in muscle cells and/or CNS cells.","english":"Provided are gene constructs that encode a microdystrophin protein for use in gene therapy. The microdystrophin gene constructs and expression cassettes were engineered for improved therapy with respect to efficacy, potency and safety to the subject when expressed by a viral vector in muscle cells and/or CNS cells."},"applicants":["REGENXBIO Inc."],"inventors":["Chunping Qiao","Devin McDougald","Ye Liu","Olivier Danos"],"filingDate":"2022-05-20","publicationDate":"2026-08-04","grantDate":"2026-08-04","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12697399B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12697399B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12697399B2","ja":"https://downloadpatent.com/ja/patent/US12697399B2"}}