{"number":"US12702650B2","kindCode":"B2","documentType":"grant","title":{"original":"Methods and compositions for treating smith-magenis syndrome","english":"Methods and compositions for treating smith-magenis syndrome"},"abstract":{"original":"The present invention is based on the finding that subanesthetic doses of N-methyl-D-aspartate (NMDA) receptor antagonists alleviate social interaction deficits associated with behavioral disorders, such as Smith-Magenis Syndrome (SMS). The invention therefore provides methods and compositions for treating SMS. Also provided are methods of selecting NMDA receptor agonists useful in alleviating social interaction deficits associated with such behavioral disorders.","english":"The present invention is based on the finding that subanesthetic doses of N-methyl-D-aspartate (NMDA) receptor antagonists alleviate social interaction deficits associated with behavioral disorders, such as Smith-Magenis Syndrome (SMS). The invention therefore provides methods and compositions for treating SMS. Also provided are methods of selecting NMDA receptor agonists useful in alleviating social interaction deficits associated with such behavioral disorders."},"applicants":["The Regents of the University of California"],"inventors":["Yimin Zou","John Scott","Sonal Thakar"],"filingDate":"2021-12-22","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702650B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702650B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702650B2","ja":"https://downloadpatent.com/ja/patent/US12702650B2"}}