{"number":"US12702657B2","kindCode":"B2","documentType":"grant","title":{"original":"Treatment and prevention of dengue disease","english":"Treatment and prevention of dengue disease"},"abstract":{"original":"The present invention relates to the use of substituted indole derivatives and substituted indoline derivatives in the manufacture of a medicament for the treatment of dengue disease in an individual infected by dengue virus or the prevention of dengue disease in an individual at risk of being infected by Dengue virus. The invention further provides a method for the treatment or the prevention of dengue in an individual at risk of being infected by Dengue virus.","english":"The present invention relates to the use of substituted indole derivatives and substituted indoline derivatives in the manufacture of a medicament for the treatment of dengue disease in an individual infected by dengue virus or the prevention of dengue disease in an individual at risk of being infected by Dengue virus. The invention further provides a method for the treatment or the prevention of dengue in an individual at risk of being infected by Dengue virus."},"applicants":["Katholieke Universiteit Leuven","Janssen Pharmaceuticals, Inc."],"inventors":["Olivia Gabriella M. GOETHALS","Bart Rudolf Romanie KESTELEYN","Bart Henri Theresia STOOPS","Jean-François BONFANTI","Tim Hugo Maria JONCKERS","Marnix VAN LOOCK","Suzanne KAPTEIN","Johan NEYTS"],"filingDate":"2022-05-14","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702657B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702657B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702657B2","ja":"https://downloadpatent.com/ja/patent/US12702657B2"}}