{"number":"US12702660B2","kindCode":"B2","documentType":"grant","title":{"original":"Method for treating cancer with an oral dosage form of an estrogen receptor-alpha inhibitor","english":"Method for treating cancer with an oral dosage form of an estrogen receptor-alpha inhibitor"},"abstract":{"original":"The present invention relates to pharmaceutical compositions comprising an inhibitor of human ERα, and methods of cancer therapy using the ERα inhibitor. In particular, described herein are dosages of H3B-6545 with defined pharmacokinetic (PK) profiles that allow the inhibitor to be efficaciously and safely administered to a human subject in need thereof.","english":"The present invention relates to pharmaceutical compositions comprising an inhibitor of human ERα, and methods of cancer therapy using the ERα inhibitor. In particular, described herein are dosages of H3B-6545 with defined pharmacokinetic (PK) profiles that allow the inhibitor to be efficaciously and safely administered to a human subject in need thereof."},"applicants":["Eisai R&D Management Co., Ltd."],"inventors":["Jianjun XIAO","Nathalie M. RIOUX","Victoria RIMKUNAS"],"filingDate":"2021-11-23","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702660B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702660B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702660B2","ja":"https://downloadpatent.com/ja/patent/US12702660B2"}}