{"number":"US12702664B2","kindCode":"B2","documentType":"grant","title":{"original":"Nicotinic acid derivative A with anti-inflammation and anti-platelet aggregation activities, and use thereof","english":"Nicotinic acid derivative A with anti-inflammation and anti-platelet aggregation activities, and use thereof"},"abstract":{"original":"The present disclosure provides a nicotinic acid derivative A with an anti-inflammation activity. The nicotinic acid derivative A has a general structural formula shown in formula (I), where R1 and R2 are different substitution sites of a main chain, and R1′ and R2′ are different substitution sites of a side chain. In the present disclosure, the nicotinic acid derivative A has desirable anti-inflammation, anti-tumor, and anti-platelet aggregation activities, and strong selectivity, and shows a remarkable clinical application value.","english":"The present disclosure provides a nicotinic acid derivative A with an anti-inflammation activity. The nicotinic acid derivative A has a general structural formula shown in formula (I), where R1 and R2 are different substitution sites of a main chain, and R1′ and R2′ are different substitution sites of a side chain. In the present disclosure, the nicotinic acid derivative A has desirable anti-inflammation, anti-tumor, and anti-platelet aggregation activities, and strong selectivity, and shows a remarkable clinical application value."},"applicants":["Chongqing Academy of Chinese Materia Medica"],"inventors":["Yong YANG","Yanlei GUO","Dajian YANG"],"filingDate":"2023-03-28","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702664B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702664B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702664B2","ja":"https://downloadpatent.com/ja/patent/US12702664B2"}}