{"number":"US12702667B2","kindCode":"B2","documentType":"grant","title":{"original":"Focal adhesion kinase inhibitor as a therapeutic agent in diabetes","english":"Focal adhesion kinase inhibitor as a therapeutic agent in diabetes"},"abstract":{"original":"It is disclosed herein that a FAK inhibitor induces conversion of acinar cells into beta cells. Methods are provided for increasing beta cell proliferation by administering an effective amount of a FAK inhibitor to a subject in need thereof. Methods are also provided for treating a subject with diabetes or at risk of developing diabetes, comprising administering to the subject a therapeutically effective amount of a FAK inhibitor.","english":"It is disclosed herein that a FAK inhibitor induces conversion of acinar cells into beta cells. Methods are provided for increasing beta cell proliferation by administering an effective amount of a FAK inhibitor to a subject in need thereof. Methods are also provided for treating a subject with diabetes or at risk of developing diabetes, comprising administering to the subject a therapeutically effective amount of a FAK inhibitor."},"applicants":["University of Pittsburgh - Of the Commonwealth System of Higher Education"],"inventors":["Farzad Esni","Jing Hu"],"filingDate":"2019-08-13","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702667B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702667B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702667B2","ja":"https://downloadpatent.com/ja/patent/US12702667B2"}}