{"number":"US12702680B2","kindCode":"B2","documentType":"grant","title":{"original":"Hydroxypropyl beta-cyclodextrin compositions and methods","english":"Hydroxypropyl beta-cyclodextrin compositions and methods"},"abstract":{"original":"This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical c…","english":"This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical c…"},"applicants":["Mandos LLC"],"inventors":["Bernardus Nicolaas Machielse","Allan Darling"],"filingDate":"2025-12-02","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702680B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702680B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702680B2","ja":"https://downloadpatent.com/ja/patent/US12702680B2"}}