{"number":"US12702681B2","kindCode":"B2","documentType":"grant","title":{"original":"Tumor immunotherapy composition based on antigen-presenting cells activated by attenuated listeria monocytogenes, preparation method therefor and application thereof","english":"Tumor immunotherapy composition based on antigen-presenting cells activated by attenuated listeria monocytogenes, preparation method therefor and application thereof"},"abstract":{"original":"A tumor immunotherapy composition based on modified cells, in particular antigen-presenting cells activated by means of attenuated Listeria monocytogenes, a preparation method therefor and an application thereof. Attenuated Listeria monocytogenes carrying a specific antigen plasmid is used to activate antigen-presenting cells, thereby activating MHC antigen presenting properties and a series of cellular immune responses in vivo so as to achieve the purpose of anti-tumor therapy.…","english":"A tumor immunotherapy composition based on modified cells, in particular antigen-presenting cells activated by means of attenuated Listeria monocytogenes, a preparation method therefor and an application thereof. Attenuated Listeria monocytogenes carrying a specific antigen plasmid is used to activate antigen-presenting cells, thereby activating MHC antigen presenting properties and a series of cellular immune responses in vivo so as to achieve the purpose of anti-tumor therapy.…"},"applicants":["Shanghai RoyalTech Med CO., Ltd","Suzhou RoyalTech Med CO., Ltd"],"inventors":["Nan DAI","Yonggang ZHAO"],"filingDate":"2021-04-23","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702681B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702681B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702681B2","ja":"https://downloadpatent.com/ja/patent/US12702681B2"}}