{"number":"US12702708B2","kindCode":"B2","documentType":"grant","title":{"original":"Presenting cell and use thereof in cell therapy","english":"Presenting cell and use thereof in cell therapy"},"abstract":{"original":"The present disclosure relates to compositions and methods for enhancing T cell response and/or CAR cell expansion and/or maintenance in vivo and/or in vitro. For example, in a method of in vivo cell expansion, the method comprises administering an effective amount of cells comprising an antigen binding molecule to a subject; and administering an effective amount of presenting cells expressing a solid tumor antigen that the binding molecule binds.","english":"The present disclosure relates to compositions and methods for enhancing T cell response and/or CAR cell expansion and/or maintenance in vivo and/or in vitro. For example, in a method of in vivo cell expansion, the method comprises administering an effective amount of cells comprising an antigen binding molecule to a subject; and administering an effective amount of presenting cells expressing a solid tumor antigen that the binding molecule binds."},"applicants":["Innovative Cellular Therapeutics, Inc.","Innovative Cellular Therapeutics Holdings, Ltd"],"inventors":["Lei Xiao","Chengfei Pu","Zhiyuan Cao","Zhao Wu","Le Tian"],"filingDate":"2020-08-21","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702708B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702708B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702708B2","ja":"https://downloadpatent.com/ja/patent/US12702708B2"}}