{"number":"US12702730B2","kindCode":"B2","documentType":"grant","title":{"original":"Engineered cartilage","english":"Engineered cartilage"},"abstract":{"original":"It is provided a method of producing high-quality engineered cartilage graft in a human of animal, such as nasal cartilage graft, comprising expanding chondrocytes and/or chondroprogenitors, e.g. autologous human nasoseptal chondrocytes (hNC,) from a donor patient by selecting expanded chondrocytes and/or chondroprogenitors by detecting the expression of at least one surfaceome protein gene or secretome protein gene, wherein the at least one surfaceome protein gene is ADGRG1, NPR3, SLC16A4, TSPAN13, FZD4 and SLC22A23 and the at least one secretome protein gene is ADGRG1, B3GNT7, COLGALT2, IGFB…","english":"It is provided a method of producing high-quality engineered cartilage graft in a human of animal, such as nasal cartilage graft, comprising expanding chondrocytes and/or chondroprogenitors, e.g. autologous human nasoseptal chondrocytes (hNC,) from a donor patient by selecting expanded chondrocytes and/or chondroprogenitors by detecting the expression of at least one surfaceome protein gene or secretome protein gene, wherein the at least one surfaceome protein gene is ADGRG1, NPR3, SLC16A4, TSPAN13, FZD4 and SLC22A23 and the at least one secretome protein gene is ADGRG1, B3GNT7, COLGALT2, IGFB…"},"applicants":["STEMCELLAGO INC."],"inventors":["Adetola Bamidele ADESIDA","Martin OSSWALD","Khalid ANSARI","Hadi SEIKALY"],"filingDate":"2022-04-27","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702730B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702730B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702730B2","ja":"https://downloadpatent.com/ja/patent/US12702730B2"}}