{"number":"US12702807B2","kindCode":"B2","documentType":"grant","title":{"original":"Methods for making microneedles using adjustment of component solubility in casting formulations","english":"Methods for making microneedles using adjustment of component solubility in casting formulations"},"abstract":{"original":"Methods are provided that involve the intentional and controlled precipitation of a drug or active agent, or a reduction of solubility of a polymer or other film-forming component of a formulation, or a combination of both methods, to improve the processes for making microneedles or other objects by casting into molds and the resulting parts produced by casting. The selective reduction in solubility of formulation components solves many problems associated with the casting of polymer formulations into molds.…","english":"Methods are provided that involve the intentional and controlled precipitation of a drug or active agent, or a reduction of solubility of a polymer or other film-forming component of a formulation, or a combination of both methods, to improve the processes for making microneedles or other objects by casting into molds and the resulting parts produced by casting. The selective reduction in solubility of formulation components solves many problems associated with the casting of polymer formulations into molds.…"},"applicants":["Georgia Tech Research Corporation"],"inventors":["Richard N. Terry","Mark R. Prausnitz"],"filingDate":"2022-04-21","publicationDate":"2026-08-11","grantDate":"2026-08-11","verifiedWithOffice":true,"pdfUrl":"https://downloadpatent.com/pdf/US12702807B2.pdf","pages":{"en":"https://downloadpatent.com/patent/US12702807B2","zh-Hant":"https://downloadpatent.com/zh-Hant/patent/US12702807B2","ja":"https://downloadpatent.com/ja/patent/US12702807B2"}}