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美國

US 12,696,884 B2

Genetically modified non-human animals expressing human EPO

US 12,696,884 B2 是美國專利商標局(USPTO)的核准專利,日期 2026-08-04。申請人:Institute for Research in Biomedicine (IRB); Yale University; Regeneron Pharmaceuticals, Inc.。PDF 可在本頁下載,未登入每天最多 5 篇。

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申請人
Institute for Research in Biomedicine (IRB); Yale University; Regeneron Pharmaceuticals, Inc.
發明人
Andrew J. Murphy; Sean Stevens; Richard Flavell; Markus Gabriel Manz; Liang Shan
公開日
2026-08-04
申請日
2023-08-10
文件種類
B2 核准公告
也寫作
US 12,696,884 B2 · US12696884 · 12696884

摘要

Genetically modified non-human animals expressing human EPO from the animal genome are provided. Also provided are methods for making non-human animals expressing human EPO from the non-human animal genome, and methods for using non-human animals expressing human EPO from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human erythropoiesis and erythrocyte function; in modeling human pathogen infection of erythrocytes; in in vivo screens for agents that modulate erythropoiesis and/or erythrocyte function, e.g.…

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專利局網站: 美國專利商標局(USPTO)

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