美國
US 12,696,884 B2
Genetically modified non-human animals expressing human EPO
US 12,696,884 B2 是美國專利商標局(USPTO)的核准專利,日期 2026-08-04。申請人:Institute for Research in Biomedicine (IRB); Yale University; Regeneron Pharmaceuticals, Inc.。PDF 可在本頁下載,未登入每天最多 5 篇。
- 申請人
- Institute for Research in Biomedicine (IRB); Yale University; Regeneron Pharmaceuticals, Inc.
- 發明人
- Andrew J. Murphy; Sean Stevens; Richard Flavell; Markus Gabriel Manz; Liang Shan
- 公開日
- 2026-08-04
- 申請日
- 2023-08-10
- 文件種類
- B2 核准公告
- 也寫作
- US 12,696,884 B2 · US12696884 · 12696884
摘要
Genetically modified non-human animals expressing human EPO from the animal genome are provided. Also provided are methods for making non-human animals expressing human EPO from the non-human animal genome, and methods for using non-human animals expressing human EPO from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human erythropoiesis and erythrocyte function; in modeling human pathogen infection of erythrocytes; in in vivo screens for agents that modulate erythropoiesis and/or erythrocyte function, e.g.…
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專利局網站: 美國專利商標局(USPTO)