美國
US 12,696,897 B2
Cryopreserving macrophages
US 12,696,897 B2 是美國專利商標局(USPTO)的核准專利,日期 2026-08-04。申請人:The University Court of The University of Edinburgh。PDF 可在本頁下載,未登入每天最多 5 篇。
- 申請人
- The University Court of The University of Edinburgh
- 發明人
- Stuart Forbes; Lara Campana; Benjamin Dwyer; John Campbell; Alasdair Fraser
- 公開日
- 2026-08-04
- 申請日
- 2022-11-25
- 文件種類
- B2 核准公告
- 也寫作
- US 12,696,897 B2 · US12696897 · 12696897
摘要
The present invention relates to a method of improving the viability of macrophages subjected to cryopreservation, particularly for macrophages which are to be used in therapy, wherein the method comprises a step of maintaining the macrophages at a temperature of 2-12° C. for at least 30 minutes during either freezing or thawing procedures. Following the holding step during cooling, a cooling rate of 1 to 5° C. is used until the macrophages in a medium are frozen. For thawing the macrophages, a warming rate of 1 to 5° C. per minute is used until a temperature of 35-37° C. is reached.…
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專利局網站: 美國專利商標局(USPTO)