美國
US 12,697,321 B2
Kv1.3 antagonists for use in the treatment of chronic and acute pain
US 12,697,321 B2 是美國專利商標局（USPTO）的核准專利，日期 2026-08-04。申請人：SEA4US - BIOTECNOLOGIA E RECURSOS MARINHOS, LDA.。PDF 可在本頁下載，未登入每天最多 5 篇。
- 申請人
- SEA4US - BIOTECNOLOGIA E RECURSOS MARINHOS, LDA.
- 發明人
- Pedro Afonso DOS SANTOS BALTAZAR DE LIMA; Beatriz SZWARC DOS SANTOS; Ana Rosa MAÇO ABREU; André Emanuel PINHEIRO BASTOS; Marisa Isabel LOPES DE SOUSA; Joana Maria MONTEIRO SERRÃO; Patrícia Isabel DA SILVEIRA MÁXIMO; Ana Maria FERREIRA DA COSTA LOURENÇO; Miguel Angelo SEGÃO MONDRAGÃO
- 公開日
- 2026-08-04
- 申請日
- 2022-01-28
- 文件種類
- B2 核准公告
- 也寫作
- US 12,697,321 B2 · US12697321 · 12697321
摘要
The present patent application relates to the use of antagonists of delayed rectifier potassium (K+) channels, more specifically Kv1.3 antagonists, as pharmaceutical agents in the treatment, prevention or reduction of both acute and chronic pain. The results and mode of action disclosed herein describe how Kv1.3 antagonists may act as analgesics through reduction of K+ currents rather than their potentiation. With regard to their high efficacy in the treatment of pain, these compounds are highly selective for slow delayed rectifier voltage-activated potassium (K+) currents.…
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專利局網站： 美國專利商標局（USPTO）