美國
US 12,697,380 B2
Attenuated virus of flavivirus virus and use thereof
US 12,697,380 B2 是美國專利商標局（USPTO）的核准專利，日期 2026-08-04。申請人：Zhejiang Free Trade Zone Hongan Base Biotechnology Co., Ltd.。PDF 可在本頁下載，未登入每天最多 5 篇。
- 申請人
- Zhejiang Free Trade Zone Hongan Base Biotechnology Co., Ltd.
- 發明人
- Bo ZHANG; Hanqing YE; Yanan ZHANG; Na LI; Qiuyan ZHANG; Chenglin DENG; Shaopeng YUAN; Shunli ZHAN; Lei GAO
- 公開日
- 2026-08-04
- 申請日
- 2023-06-21
- 文件種類
- B2 核准公告
- 也寫作
- US 12,697,380 B2 · US12697380 · 12697380
摘要
Provided are an attenuated virus of a flavivirus virus and the use thereof. The attenuated virus comprises a polyadenylic acid (poly(A)) sequence, wherein the polyadenylic acid (poly(A)) is used for replacing a part of the nucleotide sequence of a 3′ untranslated region (3′UTR) of the flavivirus virus, so that the 3′ untranslated region (3′UTR) of the attenuated virus obtained after the part of the nucleotide sequence of the flavivirus virus is replaced at least retains a 3′-end stem loop region (3′SL).…
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專利局網站： 美國專利商標局（USPTO）