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美國

US 12,697,391 B2

Bi-functional molecules to degrade circulating proteins

US 12,697,391 B2 是美國專利商標局(USPTO)的核准專利,日期 2026-08-04。申請人:YALE UNIVERSITY。PDF 可在本頁下載,未登入每天最多 5 篇。

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申請人
YALE UNIVERSITY
發明人
David Spiegel; David Caianiello
公開日
2026-08-04
申請日
2022-03-15
文件種類
B2 核准公告
也寫作
US 12,697,391 B2 · US12697391 · 12697391

摘要

Described herein is a bi-functional compound for removing macrophage migration inhibitory factor (MIF) or immunoglobin G (IgG). Further described herein is a pharmaceutical composition which comprise these bi-functional compounds. Further described herein is a method for treating disease states and/or conditions with the compounds or the composition. The disease states and/or conditions are mediated through MIF/IgG or where MIF/IgG is a contributing factor to the development and perpetuation of diseases and/or conditions, such as autoimmune diseases and cancer, among others.

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專利局網站: 美國專利商標局(USPTO)

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