美國
US 12,697,401 B2
Thrombus imaging aptamers and methods of using same
US 12,697,401 B2 是美國專利商標局（USPTO）的核准專利，日期 2026-08-04。申請人：Duke University。PDF 可在本頁下載，未登入每天最多 5 篇。
- 申請人
- Duke University
- 發明人
- Bruce A. Sullenger; Kady-Ann C. Steen-Burrell; Bethany Powell Gray
- 公開日
- 2026-08-04
- 申請日
- 2022-12-21
- 文件種類
- B2 核准公告
- 也寫作
- US 12,697,401 B2 · US12697401 · 12697401
摘要
Provided herein are imaging agents, antidotes to the imaging agents and methods of using the same to image a thrombus or blood clot or thrombin including sites of thrombin accumulation and to diagnose and treat thrombosis. The imaging agents include an aptamer capable of binding the thrombus or thrombin in particular linked to a reporter moiety. The imaging agents may be used to label the thrombus or sites of thrombin accumulation. Antidotes capable of binding to the aptamer in the imaging agent are also provided.…
這裡只列摘要開頭，完整內容在 PDF 裡。
不用登入，每天可下載 5 篇（今天還剩 5 篇）。批次下載與 OA 引證整理需免費註冊。
專利局網站： 美國專利商標局（USPTO）