美國
US 12,702,665 B2
ExoVII inhibitor and quinolone antibiotic combination useful for treating bacterial infection
US 12,702,665 B2 是美國專利商標局（USPTO）的核准專利，日期 2026-08-11。申請人：THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES。PDF 可在本頁下載，未登入每天最多 5 篇。
- 申請人
- THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES
- 發明人
- Yves Georges Pommier; Shar-yin Naomi Huang
- 公開日
- 2026-08-11
- 申請日
- 2023-06-20
- 文件種類
- B2 核准公告
- 也寫作
- US 12,702,665 B2 · US12702665 · 12702665
摘要
The disclosure provides a method of treating or preventing a bacterial infection in a subject comprising administering a therapeutically effective amount of a combination of a bacterial type IIA topoisomerase inhibitor, or a pharmaceutically acceptable salt thereof and a compound Formula I, or a pharmaceutically acceptable salt thereof, to the subject, where the compound of Formula I is (Formula (I)) where the variables, e.g. Y1, Y2, and R1-R4, are described herein. The bacterial type IIA topoisomerase inhibitor can be a quinolone antibiotic such as ciprofloxacin.
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專利局網站： 美國專利商標局（USPTO）