美國
US 12,702,706 B2
Methods of preparing anti-human papillomavirus antigen T cells
US 12,702,706 B2 是美國專利商標局（USPTO）的核准專利，日期 2026-08-11。申請人：The United States of America,as represented by the Secretary,Department of Health and Human Services。PDF 可在本頁下載，未登入每天最多 5 篇。
- 申請人
- The United States of America,as represented by the Secretary,Department of Health and Human Services
- 發明人
- Christian S. Hinrichs; Steven A. Rosenberg
- 公開日
- 2026-08-11
- 申請日
- 2024-02-01
- 文件種類
- B2 核准公告
- 也寫作
- US 12,702,706 B2 · US12702706 · 12702706
摘要
Disclosed are methods of preparing an isolated population of human papillomavirus (HPV)-specific T cells comprise dividing an HPV-positive tumor sample into multiple fragments; separately culturing the multiple fragments; obtaining T cells from the cultured multiple fragments; testing the T cells for specific autologous HPV-positive tumor recognition; selecting the T cells that exhibit specific autologous HPV-positive tumor recognition; and expanding the number of selected T cells to produce a population of HPV-specific T cells for adoptive cell therapy.…
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專利局網站： 美國專利商標局（USPTO）