美國
US 12,702,715 B2
Targeted RNA degradation allows precision repurposing of protein-targeted small molecule medicines to RNA
US 12,702,715 B2 是美國專利商標局(USPTO)的核准專利,日期 2026-08-11。申請人:University of Florida Research Foundation, Incorporated。PDF 可在本頁下載,未登入每天最多 5 篇。
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- 申請人
- University of Florida Research Foundation, Incorporated
- 發明人
- Matthew D. Disney
- 公開日
- 2026-08-11
- 申請日
- 2023-01-30
- 文件種類
- B2 核准公告
- 也寫作
- US 12,702,715 B2 · US12702715 · 12702715
摘要
The protein targeted medicine, Dovitinib, has been repurposed to target a non-coding RNA by using selection and computational drug design via Inforna. Selectivity was achieved for pre-miR-21 by endowing the medicine with the ability to recruit RNA quality control enzymes to cleave the target.
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專利局網站: 美國專利商標局(USPTO)