美國
US 12,702,722 B2
Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations
US 12,702,722 B2 是美國專利商標局(USPTO)的核准專利,日期 2026-08-11。申請人:Allen Institute。PDF 可在本頁下載,未登入每天最多 5 篇。
- 申請人
- Allen Institute
- 發明人
- Jonathan Ting; Boaz P. Levi; Bosiljka Tasic; John K. Mich; Erik Hess; Edward Sebastian Lein; Lucas T. Graybuck; Tanya Daigle; Hongkui Zeng
- 公開日
- 2026-08-11
- 申請日
- 2021-08-13
- 文件種類
- B2 核准公告
- 也寫作
- US 12,702,722 B2 · US12702722 · 12702722
摘要
Artificial expression constructs for selectively modulating gene expression in selected central nervous system cell types are described. The artificial expression constructs can be used to selectively express synthetic genes or modify gene expression in GABAergic neurons generally; and/or GABAergic neuron cell types such as lysosomal associated membrane protein 5 (Lamp5) neurons; vasoactive intestinal polypeptide-expressing (Vip) neurons; somatostatin (Sst) neurons; and/or parvalbumin (Pvalb) neuron cell types.…
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