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United States

US 12,697,308 B2

Thermostable lipid nanoparticle and methods of use thereof

US 12,697,308 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: Merck Sharp & Dohme LLC. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Merck Sharp & Dohme LLC
Inventors
Andrew Bett; Izzat T. Raheem; Jason W. Skudlarek
Publication date
2026-08-04
Filing date
2022-08-17
Document type
B2 Granted patent
Also written as
US 12,697,308 B2 · US12697308 · 12697308

Abstract

The present disclosure provides, among other things, a lipid nanoparticle adjuvant composition. The present disclosure provides pharmaceutical compositions that include a stable lipid nanoparticle adjuvant and human papillomavirus (HPV) virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82.

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Patent office website: United States Patent and Trademark Office (USPTO)

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