United States
US 12,697,321 B2
Kv1.3 antagonists for use in the treatment of chronic and acute pain
US 12,697,321 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: SEA4US - BIOTECNOLOGIA E RECURSOS MARINHOS, LDA. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- SEA4US - BIOTECNOLOGIA E RECURSOS MARINHOS, LDA.
- Inventors
- Pedro Afonso DOS SANTOS BALTAZAR DE LIMA; Beatriz SZWARC DOS SANTOS; Ana Rosa MAÇO ABREU; André Emanuel PINHEIRO BASTOS; Marisa Isabel LOPES DE SOUSA; Joana Maria MONTEIRO SERRÃO; Patrícia Isabel DA SILVEIRA MÁXIMO; Ana Maria FERREIRA DA COSTA LOURENÇO; Miguel Angelo SEGÃO MONDRAGÃO
- Publication date
- 2026-08-04
- Filing date
- 2022-01-28
- Document type
- B2 Granted patent
- Also written as
- US 12,697,321 B2 · US12697321 · 12697321
Abstract
The present patent application relates to the use of antagonists of delayed rectifier potassium (K+) channels, more specifically Kv1.3 antagonists, as pharmaceutical agents in the treatment, prevention or reduction of both acute and chronic pain. The results and mode of action disclosed herein describe how Kv1.3 antagonists may act as analgesics through reduction of K+ currents rather than their potentiation. With regard to their high efficacy in the treatment of pain, these compounds are highly selective for slow delayed rectifier voltage-activated potassium (K+) currents.…
The opening of the abstract. The full text is in the PDF.
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Patent office website: United States Patent and Trademark Office (USPTO)
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