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United States

US 12,697,331 B2

Methods of use of T-type calcium channel modulators

US 12,697,331 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: PRAXIS PRECISION MEDICINES, INC. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
PRAXIS PRECISION MEDICINES, INC.
Inventors
Kiran Reddy; Gabriel Maurice Belfort; Bernard Ravina; Marion Wittmann
Publication date
2026-08-04
Filing date
2022-10-27
Document type
B2 Granted patent
Also written as
US 12,697,331 B2 · US12697331 · 12697331

Abstract

Described herein, in part, are methods useful for preventing and/or treating a disease or condition relating to aberrant function or activity of a T-type calcium channel, such as psychiatric disorders (e.g., mood disorder (e.g., major depressive disorder)), pain, tremor (e.g., essential tremor), seizures (e.g., absence seizures), epilepsy, or an epilepsy syndrome (e.g., juvenile myoclonic epilepsy). The present invention further comprises methods for modulating the function of a T-type calcium channel and methods of administering a titrated dosage of a T-type calcium channel antagonist.

The opening of the abstract. The full text is in the PDF.

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