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United States

US 12,697,349 B2

Compositions and methods for treating RAS-mutant cancers

US 12,697,349 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: ALGEN BIOTECHNOLOGIES, INC.; MEMORIAL SLOAN KETTERING CANCER CENTER. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
ALGEN BIOTECHNOLOGIES, INC.; MEMORIAL SLOAN KETTERING CANCER CENTER
Inventors
Chun-Hao HUANG; Spencer Charles KNIGHT; Scott LOWE
Publication date
2026-08-04
Filing date
2021-10-19
Document type
B2 Granted patent
Also written as
US 12,697,349 B2 · US12697349 · 12697349

Abstract

The present disclosure relates generally to compositions and methods for the treatment of a RAS-mutant cancer. In particular, the present technology relates to administering a therapeutically effective amount of one or more TXNRD1 inhibitors to a subject diagnosed with, or at risk for a RAS-mutant cancer (e.g., RAS-mutant pancreatic cancer).

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Patent office website: United States Patent and Trademark Office (USPTO)

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