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United States

US 12,697,350 B2

Methods and compositions for treating a premature termination codon-mediated disorder

US 12,697,350 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: Tevard Biosciences, Inc. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Tevard Biosciences, Inc.
Inventors
Sean McFarland; Ying-Hsin Chen; Peter M. Eimon
Publication date
2026-08-04
Filing date
2022-04-29
Document type
B2 Granted patent
Also written as
US 12,697,350 B2 · US12697350 · 12697350

Abstract

The invention relates generally to modified tRNAs and the use of modified tRNAs to express in a mammalian cell a functional gene product encoded by a gene containing a premature termination codon and/or to treat a disease mediated by a premature termination codon, e.g., Dravet syndrome.

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Patent office website: United States Patent and Trademark Office (USPTO)

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