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United States

US 12,697,379 B2

Pegylated tetanus neurotoxins and treatment of hypotonia

US 12,697,379 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: Snoretox Pty Ltd. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Snoretox Pty Ltd
Inventors
Thomas McLean; Peter Smooker; Luke Norbury; Peter Coloe; Russell Conduit; Anthony Sasse
Publication date
2026-08-04
Filing date
2021-01-21
Document type
B2 Granted patent
Also written as
US 12,697,379 B2 · US12697379 · 12697379

Abstract

The invention relates to a composition comprising a first PEGylated tetanus neurotoxin (PEG-TeNT) comprising tetanus neurotoxin (TeNT) conjugated to polyethylene glycol (PEG) and a second TeNT. The invention also relates to various PEG-TeNTs. The invention also relates to a method of treating hypotonia using the composition or various PEG-TeNTs, and a kit comprising the composition or various PEG-TeNTs. In one embodiment, the hypotonia is obstructive sleep apnoea.

The opening of the abstract. The full text is in the PDF.

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Patent office website: United States Patent and Trademark Office (USPTO)

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