United States
US 12,697,380 B2
Attenuated virus of flavivirus virus and use thereof
US 12,697,380 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: Zhejiang Free Trade Zone Hongan Base Biotechnology Co., Ltd. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- Zhejiang Free Trade Zone Hongan Base Biotechnology Co., Ltd.
- Inventors
- Bo ZHANG; Hanqing YE; Yanan ZHANG; Na LI; Qiuyan ZHANG; Chenglin DENG; Shaopeng YUAN; Shunli ZHAN; Lei GAO
- Publication date
- 2026-08-04
- Filing date
- 2023-06-21
- Document type
- B2 Granted patent
- Also written as
- US 12,697,380 B2 · US12697380 · 12697380
Abstract
Provided are an attenuated virus of a flavivirus virus and the use thereof. The attenuated virus comprises a polyadenylic acid (poly(A)) sequence, wherein the polyadenylic acid (poly(A)) is used for replacing a part of the nucleotide sequence of a 3′ untranslated region (3′UTR) of the flavivirus virus, so that the 3′ untranslated region (3′UTR) of the attenuated virus obtained after the part of the nucleotide sequence of the flavivirus virus is replaced at least retains a 3′-end stem loop region (3′SL).…
The opening of the abstract. The full text is in the PDF.
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Patent office website: United States Patent and Trademark Office (USPTO)
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