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United States

US 12,697,387 B2

Chimeric antigen receptors targeting CD19 and use thereof

US 12,697,387 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: MILLENNIUM PHARMACEUTICALS, INC.; MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES; SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH; MEMORIAL SLOAN-KETTERING CANCER CENTER. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
MILLENNIUM PHARMACEUTICALS, INC.; MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES; SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH; MEMORIAL SLOAN-KETTERING CANCER CENTER
Inventors
Judith FEUCHT; Jorge MANSILLA-SOTO; Isabelle RIVIERE; Michel SADELAIN; Loic VINCENT; Gary SHAPIRO; Mei Rosa NG; Dan TAVARES; Xingyue HE
Publication date
2026-08-04
Filing date
2022-10-24
Document type
B2 Granted patent
Also written as
US 12,697,387 B2 · US12697387 · 12697387

Abstract

The presently disclosed subject matter provides chimeric antigen receptors (CARs) that specifically target CD19 and cells comprising such CD19-targeted CARs. The presently disclosed subject matter further provides uses of the CD19-targeted CARs for treatment, e.g., for treating blood cancer.

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Patent office website: United States Patent and Trademark Office (USPTO)

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