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United States

US 12,697,394 B2

Muscle targeting complexes and formulations for treating myotonic dystrophy

US 12,697,394 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: Dyne Therapeutics, Inc. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Dyne Therapeutics, Inc.
Inventors
Scott Hilderbrand; Timothy Weeden; John Najim; Stefano Zanotti; Romesh R. Subramanian; Mohammed T. Qatanani; Cody A. Desjardins; Kim Tang; Brendan Quinn
Publication date
2026-08-04
Filing date
2025-08-21
Document type
B2 Granted patent
Also written as
US 12,697,394 B2 · US12697394 · 12697394

Abstract

Aspects of the disclosure relate to complexes and other aspects relate to formulations (e.g., aqueous, lyophilized forms) comprising such complexes comprising an oligonucleotide (e.g., useful for targeting DMPK) covalently linked to an antibody (e.g., anti-TfR1 antibody).

The opening of the abstract. The full text is in the PDF.

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Patent office website: United States Patent and Trademark Office (USPTO)

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