United States
US 12,697,401 B2
Thrombus imaging aptamers and methods of using same
US 12,697,401 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: Duke University. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- Duke University
- Inventors
- Bruce A. Sullenger; Kady-Ann C. Steen-Burrell; Bethany Powell Gray
- Publication date
- 2026-08-04
- Filing date
- 2022-12-21
- Document type
- B2 Granted patent
- Also written as
- US 12,697,401 B2 · US12697401 · 12697401
Abstract
Provided herein are imaging agents, antidotes to the imaging agents and methods of using the same to image a thrombus or blood clot or thrombin including sites of thrombin accumulation and to diagnose and treat thrombosis. The imaging agents include an aptamer capable of binding the thrombus or thrombin in particular linked to a reporter moiety. The imaging agents may be used to label the thrombus or sites of thrombin accumulation. Antidotes capable of binding to the aptamer in the imaging agent are also provided.…
The opening of the abstract. The full text is in the PDF.
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Patent office website: United States Patent and Trademark Office (USPTO)
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