United States
US 12,697,403 B2
Small molecules for dual function positron emission tomography (PET) and cell suicide switches
US 12,697,403 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-04. Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Inventors
- Michael Farwell; Mark Sellmyer; Katheryn M. Lohith
- Publication date
- 2026-08-04
- Filing date
- 2022-01-14
- Document type
- B2 Granted patent
- Also written as
- US 12,697,403 B2 · US12697403 · 12697403
Abstract
The present invention includes an engineered cell comprising a chimeric antigen receptor (CAR) further comprising a nucleic acid molecule comprising a suicide gene comprising a ligand binding domain and a suicide domain wherein the ligand binding domain is capable of binding to radiolabeled tracer or a small molecule suicide switch.…
The opening of the abstract. The full text is in the PDF.
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Patent office website: United States Patent and Trademark Office (USPTO)
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