United States
US 12,702,122 B2
Non-human animals comprising a humanized ACE2 locus
US 12,702,122 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: Regeneron Pharmaceuticals, Inc. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- Regeneron Pharmaceuticals, Inc.
- Inventors
- Susannah Brydges; Christos Kyratsous; Alina Baum
- Publication date
- 2026-08-11
- Filing date
- 2022-12-16
- Document type
- B2 Granted patent
- Also written as
- US 12,702,122 B2 · US12702122 · 12702122
Abstract
Non-human animal cells and non-human animals comprising a humanized ACE2 locus and methods of using such non-human animal cells and non-human animals are provided. Non-human animal cells or non-human animals comprising a humanized ACE2 locus express a human ACE2 protein or a chimeric ACE2 protein, fragments of which are from human ACE2. Methods are also provided for using such non-human animals comprising a humanized ACE2 locus to assess in vivo ACE2 activity, e.g., coronavirus infection and/or the treatment or prevention thereof.
The opening of the abstract. The full text is in the PDF.
No account needed: 5 free downloads a day (5 left today). Batch downloads and Office Action citations need a free account.
Patent office website: United States Patent and Trademark Office (USPTO)
Look up another patent
Need many patents at once?
Paste a whole list of numbers. DownloadPatent finds the right version of each and packs the PDFs into one ZIP.
Sign up free