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United States

US 12,702,301 B2

System and method for assessment of neuro-inflammation using magnetic resonance imaging (MRI)

US 12,702,301 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: Wisconsin Alumni Research Foundation. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Wisconsin Alumni Research Foundation
Inventors
John-Paul Jaewoon Yu
Publication date
2026-08-11
Filing date
2025-03-07
Document type
B2 Granted patent
Also written as
US 12,702,301 B2 · US12702301 · 12702301

Abstract

A system and method are provided for non-invasively assessing neuro-inflammation in a subject. The method includes acquiring neurite orientation dispersion and density imaging (NODDI) data of the subject and processing the NODDI data to determine an orientation dispersion index (ODI) component of the NODDI data. The method also includes assessing the ODI component against one of a reference of neuro-inflammation or a prior ODI component acquired from the subject to determine one of an acute assessment or a chronic assessment of neuro-inflammation in the subject.…

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Patent office website: United States Patent and Trademark Office (USPTO)

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