United States
US 12,702,648 B2
Telodendrimer nanocarriers for monomeric amphotericin B delivery
US 12,702,648 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: The Research Foundation for the State University of New York. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- The Research Foundation for the State University of New York
- Inventors
- Juntao Luo; Xiaotian Ji; Changying Shi
- Publication date
- 2026-08-11
- Filing date
- 2024-01-30
- Document type
- B2 Granted patent
- Also written as
- US 12,702,648 B2 · US12702648 · 12702648
Abstract
Systemic fungal infections are an increasingly prevalent health problem. Amphotericin B (AmB), a hydrophobic polyene antibiotic, remains the drug of choice for life-threatening invasive fungal infections. Embodiments disclosed herein are directed telodendrimer (TD) nanocarriers having freely engineered core structures for AmB encapsulation to reduce AmB aggregation status. The reduced aggregation status correlates with the optimized antifungal activity and the attenuated hemolytic properties, as well as reduced cytotoxicity to mammalian cells.…
The opening of the abstract. The full text is in the PDF.
No account needed: 5 free downloads a day (5 left today). Batch downloads and Office Action citations need a free account.
Patent office website: United States Patent and Trademark Office (USPTO)
Look up another patent
Need many patents at once?
Paste a whole list of numbers. DownloadPatent finds the right version of each and packs the PDFs into one ZIP.
Sign up free