United States
US 12,702,650 B2
Methods and compositions for treating smith-magenis syndrome
US 12,702,650 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: The Regents of the University of California. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- The Regents of the University of California
- Inventors
- Yimin Zou; John Scott; Sonal Thakar
- Publication date
- 2026-08-11
- Filing date
- 2021-12-22
- Document type
- B2 Granted patent
- Also written as
- US 12,702,650 B2 · US12702650 · 12702650
Abstract
The present invention is based on the finding that subanesthetic doses of N-methyl-D-aspartate (NMDA) receptor antagonists alleviate social interaction deficits associated with behavioral disorders, such as Smith-Magenis Syndrome (SMS). The invention therefore provides methods and compositions for treating SMS. Also provided are methods of selecting NMDA receptor agonists useful in alleviating social interaction deficits associated with such behavioral disorders.
The opening of the abstract. The full text is in the PDF.
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