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US 12,702,664 B2

Nicotinic acid derivative A with anti-inflammation and anti-platelet aggregation activities, and use thereof

US 12,702,664 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: Chongqing Academy of Chinese Materia Medica. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Chongqing Academy of Chinese Materia Medica
Inventors
Yong YANG; Yanlei GUO; Dajian YANG
Publication date
2026-08-11
Filing date
2023-03-28
Document type
B2 Granted patent
Also written as
US 12,702,664 B2 · US12702664 · 12702664

Abstract

The present disclosure provides a nicotinic acid derivative A with an anti-inflammation activity. The nicotinic acid derivative A has a general structural formula shown in formula (I), where R1 and R2 are different substitution sites of a main chain, and R1′ and R2′ are different substitution sites of a side chain. In the present disclosure, the nicotinic acid derivative A has desirable anti-inflammation, anti-tumor, and anti-platelet aggregation activities, and strong selectivity, and shows a remarkable clinical application value.

The opening of the abstract. The full text is in the PDF.

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Patent office website: United States Patent and Trademark Office (USPTO)

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