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US 12,702,681 B2

Tumor immunotherapy composition based on antigen-presenting cells activated by attenuated listeria monocytogenes, preparation method therefor and application thereof

US 12,702,681 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: Shanghai RoyalTech Med CO., Ltd; Suzhou RoyalTech Med CO., Ltd. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Shanghai RoyalTech Med CO., Ltd; Suzhou RoyalTech Med CO., Ltd
Inventors
Nan DAI; Yonggang ZHAO
Publication date
2026-08-11
Filing date
2021-04-23
Document type
B2 Granted patent
Also written as
US 12,702,681 B2 · US12702681 · 12702681

Abstract

A tumor immunotherapy composition based on modified cells, in particular antigen-presenting cells activated by means of attenuated Listeria monocytogenes, a preparation method therefor and an application thereof. Attenuated Listeria monocytogenes carrying a specific antigen plasmid is used to activate antigen-presenting cells, thereby activating MHC antigen presenting properties and a series of cellular immune responses in vivo so as to achieve the purpose of anti-tumor therapy.…

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Patent office website: United States Patent and Trademark Office (USPTO)

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