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United States

US 12,702,695 B2

Formulated and/or co-formulated liposome compositions containing toll-like receptor (“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof

US 12,702,695 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: Nammi Therapeutics, Inc. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Nammi Therapeutics, Inc.
Inventors
David Stover; Dhruba Bharali; Bruce A. Hay; Tahmineh Safaie
Publication date
2026-08-11
Filing date
2023-03-10
Document type
B2 Granted patent
Also written as
US 12,702,695 B2 · US12702695 · 12702695

Abstract

Formulated and/or co-formulated liposomes comprising TLR prodrugs and/or TLR Lipid Moieties and methods of making the liposomes are disclosed herein. The TLR prodrug compositions comprise a drug moiety, a lipid moiety, and linkage unit that inhibit Toll-Like Receptor (e.g., TLR1/2, TLR4, and/or TLR7). The TLR prodrugs can be formulated and/or co-formulated into a liposome to provide a method of treating cancer, immunological disorders, and other disease by utilizing a targeted drug delivery vehicle.

The opening of the abstract. The full text is in the PDF.

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Patent office website: United States Patent and Trademark Office (USPTO)

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