United States
US 12,702,696 B2
Methods and composition for modulating immune response and immune homeostasis
US 12,702,696 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: President and Fellows of Harvard College; Massachusetts Institute of Technology. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- President and Fellows of Harvard College; Massachusetts Institute of Technology
- Inventors
- Carly G.K. Ziegler; Siyi Huang; Ulrich H. von Andrian; Alexander K. Shalek
- Publication date
- 2026-08-11
- Filing date
- 2020-10-16
- Document type
- B2 Granted patent
- Also written as
- US 12,702,696 B2 · US12702696 · 12702696
Abstract
The present invention discloses novel methods, uses thereof, and compositions for modulating immune responses and homeostasis in a lymph node (LN). Moreover, structural and molecular characteristics of LN-innervating sensory neurons are provided. The present invention also discloses the target cells for LN-innervating sensory neurons in LN and molecular profiles of these target cells. These molecular characteristics provide therapeutic targets for modulating immune response and immune homeostasis in LN in an animal or a human.
The opening of the abstract. The full text is in the PDF.
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Patent office website: United States Patent and Trademark Office (USPTO)
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