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United States

US 12,702,697 B2

Compositions and methods for treatment of headache disorders and neuropathic pain

US 12,702,697 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: Washington University. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
Washington University
Inventors
YU-QING CAO; ZHIYU ZHANG; RONG HU; JINTAO ZHANG; MEGAN E. CLOUD
Publication date
2026-08-11
Filing date
2022-06-17
Document type
B2 Granted patent
Also written as
US 12,702,697 B2 · US12702697 · 12702697

Abstract

Among the various aspects of the present disclosure is the provision of compositions and methods of treating or preventing various headache disorders or neuropathic pain by increasing the number of Treg cells in a subject. In particular, low dose IL-2, rapamycin, statin or Treg cell administration are shown to be useful in treating or preventing headache or neuropathic pain.

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